For my money, this is about the most exciting thing NASA is doing these days. The spacecraft has been in flight since mid 2006, and won't reach Pluto until 2015. It's a really long trip. In the meantime, even the very best Hubble generated image we have of Pluto right now is a blobby, pixelated extremely low resolution mess. There's a lot to discover here. This is on par with the pioneering craft of the 50s, 60s and 70s that were really breaking entirely new frontiers in the solar system.
The Pluto system has been in the news a lot the last few years. Of course, most famously, the definition of a planet was finally established by the IAU, and that definition excluded Pluto. In less dramatic news (politically; from a scientific standpoint this was pretty exciting) Pluto was discovered to have two moons (apart from Charon, I mean. The Pluto/Charon relationship is more akin to a double planet pairing rather than Charon being a true moon of Pluto.) Nix and Hydra. The artwork provided here is a view from Nix (or Hydra) with the rest of the Pluto system in the sky.
Perhaps most importantly of all, and entire population of Pluto-like objects (called plutinos, unsurprisingly) has come to light in the last, oh, slightly less than twenty years, and an entire massive structure, the Kuiper Belt has gone from being an obscure hypothesis to being an accepted fact even more recently. The anti-Pluto was discovered (named Orcus which is appropriate... although I'd have loved to see it called Yuggoth. Oh, well. Missed opportunity for an esoteric in-joke.)
So anyway... there won't be a lot to report on about New Horizons for quite some time, obviously, but I've already eagerly been looking forward to the results of that mission for years, and I'll continue to work myself up with interest in the next few years as well until it finally starts to send in results.